|
Pharmacological Management Of Night Vision Disturbances After Refractive Surgery
Pharmacological management of night vision disturbances after refractive surgery Results of a randomized clinical trial.
Author: Randazzo A , Nizzola F , Rossetti L , Orzalesi N , Vinciguerra P
Source: J Cataract Refract Surg, 31(9): 1764-72 2005
Summary of Research:
The purpose of the study was to evaluate the efficacy and safety of diluted aceclidine eyedrops in reducing night vision disturbances after refractive surgery. SETTING: Department of Ophthalmology, Istituto Clinico Humanitas, Rozzano-Milano, Italy.
The methods used in the research:
This double-masked randomized clinical trial included 30 patients (60 eyes) with chronic night vision disturbance after refractive surgery. Patients were randomly allocated to receive (1) placebo, (2) aceclidine 0.016%, or (3) aceclidine 0.032%. Drugs were administered once or twice daily. Anterior segment, haze, uncorrected visual acuity, best corrected visual acuity, intraocular pressure, corneal maps, and scotopic pupil size were determined at baseline and at follow-up examinations (15 and 30 days after inclusion).
LASIK: Revolutionising correction of refractive errors
LASIK, an unprecedented advancement in eye care, offers people a safe and simple opportunity to see the world clearly, minus the inconvenience or discomfort of scratched or lost contact lenses, or the blocked side vision of spectacles. In simple term LASIK is a revolutionary laser technique for correction of refractive errors.
LASIK surgery works wonders for Packers' Ferguson
Ferguson said he went to three doctors seeking a panacea for the headaches. One suggested that LASIK surgery probably would solve his eye problem and just might curb the headaches.
New, Improved LASIK Surgery
Just how much better this new ?wavefront-guided LASIK? works isn't proven yet, but it's causing excitement among eye surgeons who say the three-dimensional maps let them customize treatment in a way never before possible.
Opening Your Eyes To LASIK
More and more people are going under the laser to shed their glasses and contact lenses. So the Eye Surgery Education Council has issued new guidelines to help patients determine whether they could be candidates for laser eye surgery.
BLADE-FREE LASIK SURGERY
Are you near-sighted? Far-sighted? LASIK eye surgery could rid you of your glasses. But if fear of going under the blade is stopping you -- stop worrying. Now, a new blade-free approach.
Halos and double vision 4-step scales were built to determine subjective grading of night vision disturbance, and the root mean square (RMS) was calculated to determine objective changes in night vision disturbance.
Results & Conclusion:
The effect of diluted aceclidine started about 15 minutes after instillation and lasted for about 5 hours. No difference between the 2 dilutions could be found. Thirty-nine of 40 treated eyes showed a reduction in night vision disturbance. The mean reduction in halos and double vision grading was 1.42 +/- 0.5 (SD) and 1.14 +/- 0.4, respectively. A mean decrease in pupil size of 2.5 mm was measured. Thirty minutes after the instillation of diluted aceclidine, the topography-derived wavefront error showed a statistically significant reduction in RMS values (total, spherical, astigmatic, coma, and higher order), which was maintained for 5 hours. A transitory conjunctival hyperemia was the only side effect reported.
The researchers concluded:
Diluted aceclidine seemed to be an effective and safe treatment for night vision disturbance following refractive surgery.
|
